In the present context, it seems necessary to try to describe as precisely as possible the physiological alterations due to COVID-19. From these observations, therapeutic proposals adapted to this new disease may then be developed, particularly in the symptomatic management of the critically ill patient. It therefore seems essential to rigorously study these modifications, as they have been studied in the past for ARDS. The aim of this non-interventional study is to describe precisely the respiratory and hemodynamic changes induced by COVID-19 in mechanically ventilated patients .
Study Type
OBSERVATIONAL
Enrollment
15
Hopital Roger Salengro, CHU Lille
Lille, France
intrapulmonary shunt ratio
Time frame: during ICU stay, in the first 72 hours of mechanical ventilation initiation
Evolution of respiratory variables
Evaluation of PaO2 variation between in a high level of PEEP (15cmH2O) and a low level of PEEP (5cmH2O)
Time frame: during ICU stay, in the first 72 hours of mechanical ventilation initiation
Evolution of respiratory variables
Evaluation of PaCO2 variation between in a high level of PEEP (15cmH2O) and a low level of PEEP (5cmH2O)
Time frame: during ICU stay, in the first 72 hours of mechanical ventilation initiation
Evolution of hemodynamic stability variables
Evaluation of cardiac output variation between a high level of PEEP (15cmH2O) and a low level of PEEP (5cmH2O)
Time frame: during ICU stay, in the first 72 hours of mechanical ventilation initiation
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