Lindera Obtusiloba for Non-small Cell Lung Cancer

Inclusion Criteria: * Adults aged ≥ 20 years * Patients who have understood and signed the informed consent. * Subjects who have been confirmed histologically and radiologically for non small cell lung cancer and are scheduled to receive treatment with immune checkpoint inhibitors * Subjects whose urine HCG are negative and who have agreed with the appropriate method of contraception in case of women of childbearing potential * Subjects who can fully communicate with their medical doctor about their symptoms or quality of life and who can fill out questionnaires * Subjects who can follow up during the clinical trial * Eastern Cooperative Oncology Group (ECOG) performance status score ≤ 2 * Hemoglobin ≥ 9g/dL Exclusion Criteria: * Subjects who are pregnant, breastfeeding, planning to become pregnant or women of childbearing potential who do not agree with the appropriate method of contraception * Subjects who have symptomatic and uncontrolled brain or central nervous system metastasis * Subjects who complain of uncontrolled pain despite using analgesics * Diastolic Blood Pressure\>100mmHg or Systolic Blood Pressure\>160mmHg * Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels higher than 2.5 times the upper limit for normal * Creatinine level higher than 1.5 times the upper limit for normal * Subjects who have participated in other clinical trials within 1 months * Subjects with a history of serious drug allergies or who have hypersensitivity to the Investigational Product (the main ingredient and its components) * Subjects with autoimmune diseases * Subjects who have alcoholism or drug dependence * Subjects who have cognitive impairment or psychiatric problems * Subjects who have undergone surgery within 2 weeks * Subjects who took other herbal medicine or other medicines within 4 weeks * Subjects who have a medical condition that is likely to affect results or who are determined to be inappropriate to participate in this clinical trial at the investigator