INTRODUCTION: The complexity of the pathophysiology of heterogeneous diseases such as heart failure and obstructive pulmonary disease causes a different approach to these diseases or with a view as much as a better understanding of the same situations, with which the clinical profile of patients who are associated with an association is. It is known that regular physical training promotes progressive improvements in exercise tolerance, in the pulmonary ventilation / perfusion ratio and in respiratory function by strengthening. OBJECTIVE: To compare the effects of high-intensity interval training and continuous aerobic exercise, with peripheral endothelial function, brain natriuretic peptide levels, maximum exercise tolerance, distribution of lung volumes and quality of life of patients with obstructive pulmonary disease associated with heart failure. METHODS: This is a clinical, controlled, randomized and blinded trial. Peripheral endothelial function, tolerance to maximum and submaximal exercise, distribution of lung volumes, quality of life, presence of symptoms of depression and perception of clinical change will be evaluated. EXPECTED RESULTS: Incorporate into the care of these patients, new effective therapeutic approaches, of low cost and with greater technical and scientific evidence.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Exercise with high-intensity intervals followed by active rest
Interval Moderate-intensity aerobic training without intervals
Federal University of Pernambuco
Recife, Pernambuco, Brazil
Exercise tolerance
Evaluated by the cardiopulmonary exercise test by measuring the maximum oxygen consumption.
Time frame: 24 weeks
Peripheral endothelial function
Evaluated by the peripheral arterial tonometry using the EndoPat 2000 device
Time frame: 24 weeks
Quality of life assessment: Short Form-36 questionnaire
Evaluated by the Short Form-36 questionnaire
Time frame: 24 weeks
Perception of clinical change
Evaluated by the Patient Global Impression of Change Scale which is a one-dimensional measure in which individuals can rate their associated improvement on a 7-item scale ranging from "1 = no changes" to "7 = much better".
Time frame: 24 weeks
Distance covered in the six-minute walk test
Evaluated by the six-minute walk test
Time frame: 24 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.