Effect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Spontaneous Vaginal Delivery

Federico II University122 enrolled

Overview

Policies for timing of cord clamping vary, with early cord clamping generally carried out in the first 60 seconds aLer birth, whereas latercord clamping usually involves clamping the umbilical cord greater than one minute after the birth or when cord pulsation has ceased

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

122

Conditions

Post Partum Hemorrhage

Interventions

delayed cord clampingOTHER

delayed cord clamping

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * singleton pregnancy * at term * cephalic presentation * spontaneous labor * spontaneous vaginal delivery Exclusion Criteria: * multiple gestation * preterm gestation * induced labor * operative delivery * hypertension or preeclampsia * fetal anomaly * abnormal placentation * planned cord blood banking * maternal bleeding disorder

Locations (1)

Casa di Cura Accreditata Fabia Mater, Rome, Italy

Rome, Roma, Italy

Outcomes

Primary Outcomes

change in maternal hemoglobin level on post delivery day 1 compared with the predelivery hemoglobin level

The primary outcome was an objective measure of maternal blood loss: the change in maternal hemoglobin level on postdelivery day 1 compared with the predelivery hemoglobin level.

Time frame: day 1 after delivery

Secondary Outcomes

postpartum hemorrhage

defined as estimated blood loss\>500cc

Time frame: at the time of delivery

uterotonic administration

Time frame: at the time of delivery

need for blood transfusion

Time frame: at the time of delivery

jaundice

neonatal jaundice

Time frame: day 10 of life

Data from ClinicalTrials.gov

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