Acute kidney injury (AKI) has been identified as an independent risk factor for in-hospital mortality. The present study aims to investigate the incidence of AKI and renal recovery of inpatients diagnosed with COVID-19.
Beginning in December 2019, a novel coronavirus, designated as severe acute respiratory distress coronavirus 2 (SARS-CoV-2), has caused an international outbreak of respiratory illness termed coronavirus disease 2019 (COVID-19). Although the clinical manifestations of COVID-19 are dominated by respiratory symptoms, some patients show severe kidney abnormalities. Acute kidney injury (AKI) has been identified as an independent risk factor for in-hospital mortality. The present study aims to investigate the incidence of AKI and renal recovery of inpatients diagnosed with COVID-19.
Study Type
OBSERVATIONAL
Enrollment
900
University Hospital Giessen and Marburg, Giessen
Giessen, Hesse, Germany
Incidence of AKI
Serial assessment of serum creatinine and urine output
Time frame: 30 days post-hospital admission
Cystatin C as indicator of mortality
All-cause mortality
Time frame: 30 days post-hospital admission
Cystatin C as indicator of renal disease
AKI and acute kidney disease (AKD)
Time frame: 30 days post-hospital admission
Cystatin C as indicator of respiratory illness
Ventilator-free days
Time frame: 30 days post-hospital admission
Cystatin C as indicator of disease severity
Rate of intensive care unit admission
Time frame: 30 days post-hospital admission
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