Since December 2019, an international outbreak of respiratory illnesses caused by SARS-CoV-2 called covid-19 has become a global challenge. In France, while the first cases were reported in January, more than 20 000 cases were confirmed at end of March. Early estimations from epidemiological data seem to show that 18-20% of patients with confirmed covid-19 are admitted in an intensive care unit (ICU). Patients with chronic inflammatory rheumatism, auto-immune or auto-inflammatory rare and non-rare diseases are susceptible to severe covid-19 (i.e ICU) due to the specific therapeutic management of their illness (corticosteroid, immunosuppressive and immunomodulatory drugs,..). No data are available for this particular population in France. This retrospective multicentre observational study aims to evaluate the frequency of severe forms of covid-19 and risk factors associated with specific outcomes in covid-19 in patients with chronic inflammatory rheumatism, auto-immune or auto-inflammatory rare and non-rare diseases.
Study Type
OBSERVATIONAL
Enrollment
13,770
Hôpital Huriez
Lille, France
RECRUITINGProportion of patients presenting a severe form of covid-19 requiring an intensive care unit admission or leading to death
Time frame: From Baseline up to Day 21 after first symptoms of covid-19
Proportion of patients who die from a severe form of covid-19
Time frame: From Baseline up to Day 21 after first symptoms of covid-19
Proportion of patients who present an history of diabetes according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present obesity (validated by Body Mass Index value > 30 kg/cm2)
Time frame: At the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present an history of Chronic Pulmonary Obstructive Disease according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present an history of Asthma according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present an history of Hypertension according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present an history of cardiac disease according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present an history of Pulmonary Interstitial Disease according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present an history of stroke according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present an history of angiotensin-converting-enzyme inhibitor according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
Proportion of patients who present an history of cancer according to medical records
Time frame: Before the set-up of first symptoms of covid-19 (Baseline visit)
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