In late December 2019, an emerging disease due to a novel coronavirus (named SARS-CoV-2) rapidly spread in China and outside. France is currently facing the COVID-19 wave with more than 131 863 confirmed cases and almost 25 201 deaths. Systems of care have been reorganized in an effort to preserve hospital bed capacity, resources, and avoid exposure of patients to the hospital environment where COVID-19 may be more prevalent. Therefore, elective procedures of catheterization and programmed hospitalizations have been delayed. However, a significant proportion of procedures within the catheterization laboratory such as ST-elevation myocardial infarction (STEMI), non ST elevation myocardial infarction or unstable angina are mandatory and cannot be postponed. Surprisingly, invasive cardiologist noticed a drop in STEMI volume without reliable data to confirm this impression. Furthermore, a recent single center report in Hong Kong pointed out longer delays of taking care when compared to patients with STEMI treated with percutaneous intervention the previous year. These data are at major concern because delay in seeking care or not seeking care could have detrimental impact on outcomes.
The aim of this study is to investigate the rates and characteristics of patients presenting with acute myocardial infarction between march 1, 2020 to May 31, 2020 and compared those data with those of this year (march 1, 2019 to May 31, 2019). The following elements will aslo been collected: * Clinical presentation * Mode of admission (SAMU (Service d'Aide Médicale Urgente in French ie Emergency Medical Aid Service) / emergency department / in hospital) * Call for SAMU : delay, number of calls, response * Thrombolysis * Delays (symptom onset to first medical contact / door to balloon) * Final Result : TIMI (Thrombolysis In Myocardial Infarction) * COVID-19 status if known * Underlying known ischemic cardiopathy * ECG (electrocardiogram) Q waves. * Complication after PCI (Percutaneous Coronary Intervention): Discharged date, LVEF (Left Ventricular Ejection Fraction), ventricular tachycardia Data will be collected through all participating centers under the supervision of the cath lab director.
Study Type
OBSERVATIONAL
Enrollment
6,332
Hôpital Universitaire Carémeau
Nîmes, France
The primary endpoint is a composite of death from all causes and mechanical complications of acute myocardial infarction (MI)
Free wall rupture, acute ischemic mitral regurgitation, ventricular septal rupture
Time frame: 3 months (between March 1 to May 31, 2019 and between March 1 to May 31, 2020 )
Rates of patients presenting with acute myocardial infarction
Compare the number of patients presenting to cardiology department with acute myocardial infarction in 2019 versus in 2020
Time frame: 3 months (between March 1 to May 31, 2019 and between March 1 to May 31, 2020 )
Patient profile during admission for acute myocardial infarction
Correlation between clinical patient profile and the degree of affection of regions by COVID-19
Time frame: 3 months (between March 1 to May 31
Medical care times analysis
Correlation between the delay between onset of symptoms - first medical contact - coronary angiography room and the degree of affection of regions by COVID-19
Time frame: 3 months (between March 1 to May 31)
Medical care times analysis
Delay in minutes from symptom onset and STEMI (ST Segment Elevation Myocardial Infarction) diagnosis; and delay in minutes from onset of symptoms and primary PCI (percutaneous coronary intervention)
Time frame: 3 months (between March 1 to May 31, 2019 and between March 1 to May 31, 2020 )
Clinical evolution of patients
Correlation between the fate of patient and the degree of affection of regions by COVID-19: Number of days in cardiology department, Left Ventricular Ejection Fraction at discharge, presence of hemodynamic complications, presence of mechanical complications, transfer to intensive care unit, infection with COVID-19 during hospitalization, living status at discharge
Time frame: 3 months (between March 1 to May 31)
Clinical evolution of patients
Number of in hospital outcomes including orotracheal intubation, cardiogenic shock, arrhythmias (ventricular tachycardia of ventricular fibrillation) and in hospital cardiac arrest
Time frame: 3 months (between March 1 to May 31, 2019 and between March 1 to May 31, 2020 )
STEMI (ST Segment Elevation Myocardial Infarction) admissions incidence rates
Number of patient admitted in cardiology department with STEMI (ST Segment Elevation Myocardial Infarction)
Time frame: 3 months (between March 1 to May 31, 2019 and between March 1 to May 31, 2020 )
Proportion of patients who underwent systemic thrombolysis
Correlation between the number of patients who underwent systemic thrombolysis and the degree of affection of regions by COVID-19
Time frame: 3 months (between March 1 to May 31)
Proportion of patients infected with COVID-19
Number of patient admitted in cardiology department for acute myocardial infarction infected with COVID-19
Time frame: 3 months (between March 1 to May 31)
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