Propensity Score Matched Comparison of HMP vs. SCS in Kidney Transplantation

Medical University Innsbruck347 enrolled

Overview

Hypothermic machine perfusion (HMP) is considered superior to static cold storage (SCS) in kidney transplantation, but the true benefit in the real-world experience remains incompletely understood. The aim of our study is to investigate the real-world impact of HMP on kidney graft function after deceased donor kidney transplant in an HMP cohort propensity score matched with SCS. Propensity score matching will be based on CIT, ECD, gender mismatch, CMV mismatch, re-TX and ET-senior program with a caliper of 0.05

Study Type

OBSERVATIONAL

Enrollment

347

Conditions

Delayed Graft Function

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * single kidney transplantation from a deceased donor at Medical University of Innsbruck between 08/2015 and 12/2019 Exclusion Criteria: * combined kidney transplantation with an other organ * living donor kidney transplantation

Locations (1)

Medical University of Innsbruck

Innsbruck, Tyrol, Austria

Outcomes

Primary Outcomes

Delayed graft function (DGF)

DGF was defined as the need for at least one dialysis within the first seven days after transplant with the exception of dialysis for hyperkalemia or hypervolemia within the first 12 hours post-transplant

Time frame: 7 days post transplant

Secondary Outcomes

graft survival

24 month graft survival

Time frame: 24 months post transplant

Data from ClinicalTrials.gov

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