The investigators hypothesize that those with respiratory failure due to COVID-19 will have different burdens of mental and physical disability than those with respiratory failure who do not have COVID-19. Detecting these potential differences will lay an important foundation for treating long term sequelae of respiratory failure in these two cohorts.
The aim of this proposal to is to understand the extent and degree of physical disability, psychological sequelae, and cognitive dysfunction survivors of COVID-19 related critical illness will have upon hospital discharge, 6 months, and up to one year post discharge. These outcomes of interest will be evaluated prospectively. The investigators will perform these measures in Covid-19 patients with respiratory failure and compare them to non-Covid-19 patients with respiratory failure. The investigators also seek to determine the risk factors of these long-term complications in order to guide providers as to which patients should be screened for these deficits. Finally, the investigators will examine the association of various critical care interventions such as invasive versus noninvasive mechanical ventilation or use of sedatives and their effects on disability and cognitive dysfunction.
Study Type
OBSERVATIONAL
Enrollment
500
Physical disability assessment tool
Psychological Sequelae assessment tool
Psychological Sequelae assessment tool
University of Chicago Medical Center
Chicago, Illinois, United States
Quality of Life score
SF-36 score
Time frame: up to 12 months after discharge
cognitive dysfunction
Montreal Cognitive Assessment (MoCA) score
Time frame: up to 12 months after discharge
Functional Status Score
(FSS-ICU)
Time frame: up to 12 months after discharge
Physical Disability
MRC neuromuscular Assessment
Time frame: up to 12 months after discharge
Psychological Sequelae
Impact Event Score
Time frame: up to 12 months after discharge
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