Precision Immunology to Determine the Immune Response in Patients With COVID-19

University of Bonn200 enrolled

Overview

To better understand the immune response to SARS-CoV-2 infection, we devised a precision immunology approach to systematically study the immune function of different patient cohorts

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

SARS-CoV 2 COVID

Interventions

Blood drawOTHER

serial blood draw and subsequent deep immune phenotyping analysis, (ii.) immune activation assays, (iii.) transcriptome and (iv.) epigenome analysis in an overarching (v.) bioinformatics data analysis

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * SARS-Cov2 positive PCR Exclusion Criteria: * pregnancy

Locations (1)

University Hospital Bonn

Bonn, Germany

RECRUITING

Outcomes

Primary Outcomes

Immune response

Immune response of whole blood stimulation assay with various immune activators will be measured by FACS and multiplex Assay

Time frame: 4 weeks

Central Contacts

Christian Bode, MD

CONTACT

+49228287 christian.bode@ukbonn.de

Folkert Steinhagen, MD

CONTACT

+49228287 Folkert.Steinhagen@ukbonn.de

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.