Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the current pandemic of coronavirus disease (COVID-19) that can lead to respiratory failure requiring oxygen therapy. Some patients develop acute respiratory distress syndrome (ARDS) and may die despite intensive care therapy. Currently it is unknown a) how fast patients recover after being discharged from hospital and b) what underlying predictors may influence recovery.
Study aims: * To evaluate subjective and objective recovery after discharge from hospital in patients with respiratory failure due to COVID-19. * To identify risk factors for COVID-19 associated respiratory failure and prolonged recovery
Study Type
OBSERVATIONAL
Enrollment
58
Questionnaires targeting health-related quality-of-life, symptoms, anxiety and depression
University Hospital Zurich
Zurich, Switzerland
Health-related quality-of-life
European Quality of Life - 5 Dimensions - 5 Levels Instrument (EQ-5D-5L). Scoring: Index ranges from 1 to \<0, with lower scores indicating more limitations.
Time frame: 3 months
Anxiety and depression
Hospital Axiety and Depression Score (HADS). Scoring: Scores range from 0 to 42, with higher scores indicating more anxiety or depression symptoms.
Time frame: 3 months
Symptom burden
COPD Assessment Test (CAT). Scoring: Scores range from 0-40, with higher scores indicating more symptoms due to respiratory limitations.
Time frame: 3 months
Spirometry
Forced expiratory volume in one second (FEV1) in liters and percent predicted.
Time frame: 1 month
Spirometry
Forced vital capacity (FVC) in liters and percent predicted.
Time frame: 1 month
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