Efficacy of tranexamic acid on blood loss during percutaneous nephrolithotomy. a double-blind, placebo-controlled randomized clinical trial.
To evaluate whether intravenous tranexamic acid or tranexamic acid in the irrigation fluid in percutaneous nephrolithotomy (PCNL) in reducing bleeding during and after PCNL.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
200
hemostatics use
Kafrelsheikh faculty of medicine
Kafr ash Shaykh, Kafrelsheikh, Egypt
RECRUITINGTo assess the value of tranexamic acid
To compare the efficacy and safety of 0.1% IV tranexamic acid versus inside the irrigant fluid tranexamic acid in reducing blood loss during PCNL. Moreover, to assess the adverse events of tranexamic acid.
Time frame: 12 months
Hemoglobin drop post PCNL.
Assess fall percentage in hemoglobin drop.
Time frame: 12 months
Requirement of blood transfusion post PCNL.
assess the total blood loss and requirement of blood transfusion post PCNL.
Time frame: 12 months
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