Effects of Transcutaneous Electrical Nerve Stimulation on Chemotherapy-Induced Peripheral Neuropathy

Inclusion Criteria: * Have completed treatment with a platinum agent, taxane, vinca alkaloid, or bortezomib at least 3 months prior to registration * Have a clinical diagnosis of CIPN from their physician or physician designee based on the following criteria: bilateral (i.e., present on both sides of the body), abnormal sensory symptoms in their feet or legs (e.g., hot/burning pain, sharp/shooting pain, numbness, tingling, cramping) * Report at least 1 non-painful symptom associated with CIPN in their lower limbs (e.g., tingling, burning that isn't reported as painful, numbness) * Report at least 2 of the following symptoms in their lower limbs (at their worst) as at least 4 out of 10 on a 0 - 10 NRS: hot/burning pain, sharp/shooting pain, numbness, tingling, cramping at visit 1 (i.e., week -1). Use the CIPN Symptom Inventory - week recall form (questions 1-5 ONLY) to assess these symptoms at screening * Be willing and able not to start any new analgesic medications or change the dosages of any current analgesic medications (except acetaminophen \[Tylenol\] or non-steroidal anti-inflammatory drugs \[NSAIDs\] \[i.e., ibuprofen (Advil, Motrin), naproxen (Aleve)\]) for the duration of the study * Be able to read English (i.e., is not illiterate, can speak English, and is not blind) * Have access to a smart phone or device with an Apple or Android operating system that can be used to access the TENS device's application (App) and ability to connect to the internet on a daily basis during the trial Exclusion Criteria: * Have pre-existing neuropathy of any cause documented in their medical record prior to the start of chemotherapy or respond "yes" to the question "Did you have frequent numbness, tingling, sharp/shooting pain, hot/burning pain, or cramping in your feet before you started your chemotherapy?" * Have unilateral CIPN symptoms (i.e., symptoms occur on predominantly only one side of the body) * Be currently using a TENS device for any other reason * Be currently taking, or have taken in the past 3 months, medications known to cause neuropathy in a significant portion of patients * Have an acute and symptomatic lower extremity deep vein thrombosis (DVT) (treated DVT with resolution of symptoms is acceptable for enrollment) * Lower extremity edema that is 2+ or greater (i.e., slight indentation that takes less than 15 seconds to rebound) * Have started a new prescription pain medication or altered dosages of a prescription pain medication within the last 2 weeks * Have lower extremity wounds or ulcers * Have a cardiac pace maker or defibrillator * Have epilepsy * Have a leg that is too small or too large for the TENS device to fit securely * Have missing lower limbs or amputations * Have impaired decision making capacity (i.e., requires a legally authorized representative or health care proxy) * Be pregnant or planning to get pregnant before expected completion of the study