Development of a Molecular Diagnostic Strategy for SARS-CoV2 Based on Saliva in the Context of the COVID-19 Pandemic

University Hospital, Rouen130 enrolled

Overview

The objective of the study is to develop and validate a molecular diagnostic strategy (RT-ddPCR multiplex) of COVID-19 based on a saliva sample and alternative to the RT-qPCR method, in order to : 1. to compensate for the risk of a shortage of diagnostic kits, reagents and materials necessary for molecular diagnosis; 2. to increase the molecular diagnostic capacity of COVID-19 at the Rouen University Hospital; 3. and to have a method compatible with screening extended to populations at risk.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

130

Conditions

COVID RT-ddPCR Multiplex

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Person aged over 18 years presenting to the COVID-19 consultation of the Rouen University Hospital for screening * Person affiliated to a social security scheme Exclusion Criteria: * Person objecting to participation in the research after reading information * Person under the protection of justice, * Person deprived of their liberty by administrative or judicial decision (guardianship, curatorship, etc.) * Patient under guardianship or curatorship

Outcomes

Primary Outcomes

Number of positive patient using saliva method compared to number of positive patient using standard method

Time frame: One hour

Number of negative patient using saliva method compared to number of negative patient using standard method