Variability of Heart Rate as a Marker of Complication of Colorectal Surgery

Centre Hospitalier Universitaire de Nīmes117 enrolled

Overview

Heart rate variability reflects the autonomic nervous system on the intrinsic activity of sinus node cells. Sympathetic hyperactivity is an adaptation to stress, while parasympathetic hyperactivity is present at rest. Thus, any variability in the heart frequency rate reflects variations in sympathetic and parasympathetic components in the autonomic nervous system. Failure to return to normal or a reduction in the variability of the heart rate in the postoperative period is correlated with complications in colorectal surgery.

Study Type

OBSERVATIONAL

Enrollment

117

Conditions

Surgery--Complications

Interventions

Heart Rate VariabilityDIAGNOSTIC_TEST

Heart rate and RR interval Post-anonymized analysis of heart rate variability using the KUBIOS software

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients operated for a scheduled colorectal resection due to cancer, diverticulitis, or Chronic Inflammatory Bowel Disease, * American Society of Anesthesiologists score 1-2 * The patient must have given their free and informed consent and signed the consent form * The patient must be a member or beneficiary of a health insurance plan Exclusion Criteria: * Patient taking antidepressants, antipsychotics, antihypertensive beta blocker type, anti-arythmic or oral contraception * Uncontrolled diabetes or associated with a neuropathy * Arrhythmias and conduction disturbances, , coronaropathy and heart failure, kidney failure * Neuropathies * Pacemaker or defibrillator * The subject is participating in another interventional study, or is in a period of exclusion determined by a previous study * The subject refuses to sign the consent * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship

Outcomes

Primary Outcomes

Rate of variability of the heart rate between Day-1 to Day 7

Measured by power spectral density; ratio of the high to low frequencies

Time frame: Day 7

Correlation between the rate of variability of the heart rate between Day-1 to Day 7and anastomotic fistula diagnosed according to Center for Diseases Control criteria after scheduled colorectal surgery

Abdominal-pelvic imagery