Skin Fluorescent Imaging (SFI) System in Patients With Nevi

Inclusion Criteria: In order to be eligible to participate in this study a subject must meet all of the following criteria: * Provide a signed and dated informed consent form * Age ≥ 18 years old * Subjects must present with suspicious atypical nevi scheduled for a biopsy\* * Nevi with at least 1 cm of skin surrounding the mole * Nevi must be accessible to the SFI imaging device * Excisional or a tangential excision with a dept of 1 to 2 mm biopsy will be performed for the mole tested within 21 days of testing. * Nevi with clinically atypical features Only 1 mole per eligible subject will be SFI tested in this study. \*NOTE: a subset of patients (\~10%) with benign nevi (by clinical observation) who wish to have nevi removed for cosmetic reasons will be enrolled as negative controls. Exclusion Criteria: An individual who meets any of the following criteria will be excluded from participation in this study: * Subjects who are younger than 18 years old * Lesions that are consistent with \- Features of Keratosis and keratin plugs * Basal Cell Carcinoma * Squamous Cell Carcinoma * Challenging anatomical location (e.g., body cervices) * Subjects with nevi that fit the inclusion criteria but are: * Less than 1 cm from the eyes * On the palms of the hands or soles of the feet * Associated with scar tissue * Mucosal lesions * Ulcerated lesions / breached skin * Lesions with some clinical certainty of being melanomas (large, dark, etc.) * Any nevi with ink marking including tattoos, on or adjacent to the nevi * Lesions treated with local anesthesia such as lidocaine prior to enrollment * Lesions larger than 20 mm or too large to allow imaging * Subject is known to be pregnant * Subject who is mentally or physically unable to comply with all aspects of the study * Subject who is undergoing systemic cancer treatment within 6 months of SFI testing * Subject with hypersensitivity to any of the SFI reagents * Subjects with known sensitivity to fluorescent dyes * Any subject who has previously participated (testing to biopsy) in SFI 003