The project will evaluate thermoregulatory processes among individuals with and without first-episode psychosis.
The project will evaluate thermoregulatory processes among individuals with and without first-episode psychosis. Aim 1: Assess whether individuals with first-episode psychosis have differences in mean temperature and diurnal temperature variation as compared to individuals without psychosis. Aim 2: Examine whether mean temperature and temperature variation during periods of rest and activity are different between individuals with first-episode psychosis versus people without psychosis. Aim 3: Explore the association between current core body temperature and current ratings of psychotic symptomatology among individuals with first-episode psychosis. Study participants will complete baseline assessments (e.g., symptoms, functioning, and sleep) and then complete a 24-36 hour ambulatory assessment period in which core temperature, activity, sleep, and heart rate variability will be tracked continuously and symptom severity will be assessed sporadically using a symptom rating app on their smart phone. .Then they will complete a second study visit to repeat baseline assessments.
Study Type
OBSERVATIONAL
Harding Hospital
Columbus, Ohio, United States
Differences in mean temperature and diurnal temperature variation
Differences in mean temperature and diurnal temperature variation in individuals with first-episode psychosis as compared to individuals without psychosis.
Time frame: 24 hour intervals
Differences in mean temperature and temperature variation during periods of rest and activity
Differences in mean temperature and temperature variation during periods of rest and activity between individuals with first-episode psychosis versus people without psychosis.
Time frame: 24 hour intervals
Association of core body temperature and ratings of psychotic symptomatology in FEP
Association between core body temperature and ratings of psychotic symptomatology among individuals with first-episode psychosis.
Time frame: 24 hour intervals
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