The authors conducted a case series to determine the outcomes of treatment of root surface caries lesions when the teeth were treated topically with 38% silver diamine fluoride.
The study is a prospective, single center case series. The cases were consecutive. Participation was offered to every patient who qualified based on age and the presence of an active lesion in a root surfaces, in a furcation, or under an individual crown or crown abutment for a fixed prosthesis. The study was conducted at the dental clinic of the Roseman College of Dental Medicine in South Jordan, Utah. The University of California, San Francisco protocol for applying topical silver diamine fluoride was adapted for use with these patients. Lesions were flushed with water and then dried with compressed air, isolated with cotton rolls, and then 38% silver diamine fluoride (Advantage Arrest, Elevate Oral Care, West Palm Beach, FL) was applied repeatedly for two minutes with the manufacturer supplied dental applicator. The silver diamine fluoride was stored under the manufacturer's recommended conditions. If the patient complained about the taste, the lesion was coated with sodium fluoride varnish. All of the lesions were reevaluated for dental caries lesion activity about every six months and retreated regardless of their arrest status. Follow-up was for 30 months or until loss to follow-up.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
63
Dental caries arrest medication
Dental caries lesion activity 1
Nyvad score based on visual/tactile examination
Time frame: 6-12 months
Dental caries lesion activity 2
Nyvad score based on visual/tactile examination
Time frame: <6 months
Dental caries lesion activity 3
Nyvad score based on visual/tactile examination
Time frame: 12-18 months
Dental caries lesion activity 4
Nyvad score based on visual/tactile examination
Time frame: 18-24 months
Dental caries lesion activity 5
Nyvad score based on visual/tactile examination
Time frame: 24-30 months
Caries lesion fluorescence 1
Laser fluorescence measurement at the surface of the lesion
Time frame: <6 months
Caries lesion fluorescence 2
Laser fluorescence measurement at the surface of the lesion
Time frame: 6-12 months
Caries lesion fluorescence 3
Laser fluorescence measurement at the surface of the lesion
Time frame: 12-18 months
Caries lesion fluorescence 4
Laser fluorescence measurement at the surface of the lesion
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Time frame: 18-24 months
Caries lesion fluorescence 5
Laser fluorescence measurement at the surface of the lesion
Time frame: 24-30 months