Prophylactic Benefit of Hydroxychloroquine in COVID-19 Cases With Mild to Moderate Symptoms and in Healthcare Workers With High Exposure Risk

Inclusion Criteria: * Male or female over 18 years of age at the time of enrollment * COVID-19 test positive patients with mild-moderate symptoms including fever \>37.50 F * Consecutive consenting staff at ICU, ER and COVID-19 unit that have never been diagnosed with COVID-19 Exclusion Criteria: * Exclusion criteria: * Hepatic cirrhosis or active hepatitis B or C * Severe renal disease * Hospitalized for severe symptoms of COVID-19 (ARDS), on mechanical ventilation or ECMO * Contraindication to HCQ * Using HCQ for some other condition (i.e. SLE, rheumatoid arthritis) * Pregnant or breast feeding * Known history of long QT syndrome (QTc \>500 ms on electrocardiogram) * Seizure disorder * Body weight \<50kg * Psoriasis * Unwilling to provide informed consent