Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy

Aix Marseille Université477 enrolled

Overview

With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia. The aim of this study was to investigate in patients undergoing total thyroidectomy whether serum calcium and/or PTH levels can predict hypoparathyroidism.

Our study consists of analyzing the calcium (mmol/l) and PTH (pmol/l) levels on the first postoperative day. Postoperative treatment with calcium and vitamin D and the length of hospital stay is also taken into consideration. We also analyze post-operative complications.

Study Type

OBSERVATIONAL

Enrollment

477

Conditions

Hypoparathyroidism

Interventions

analysis of hypocalcemiaOTHER

analysis of postoperative calcium and PTH levels

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: • Total thyroidectomy Exclusion Criteria: * concomitant parathyroidectomy for primary hyperparathyroidism * lobectomy only * completion thyroidectomy * central and lateral neck dissection * patients with calcium and/or vitamin D supplementation prior surgery * patients with known and significant osteoporosis and renal failure

Locations (1)

Conception Hospital

Marseille, France

Outcomes

Primary Outcomes

calcium and PTH thresholds

For all 477 patients postoperative calcium and PTH levels and treatment with calcium and vitamin D will be analyzed. Objective is to identify the calcium and PTH thresholds at which the patient after total thyroidectomy can be discharged without risk of hypocalcemia.

Time frame: one years

Data from ClinicalTrials.gov

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