Patients older than 60 years are more and more transplanted. Comprehensive geriatric assessment (CGA) have been developed and are currently used in patients with cancer, it has been correlated with the prognosis. There is still few data in transplanted patients and the aim of this study is to assess these patients before and after transplantation in order to monitor their general health and quality of life (QOF) and correlate them to the prognostic.
Study Type
OBSERVATIONAL
Enrollment
205
Questionnaires on nutritional status, autonomy and quality of life
CHU Amiens
Amiens, France
CHU Angers
Angers, France
CHU Besancon
Besançon, France
Overall survival
Time frame: at one year post allogeneic hematopoietic stem cell transplantation
Overall survival
Time frame: at two years post allogeneic hematopoietic stem cell transplantation
Morbidity Index
Time frame: at one year
Morbidity Index
Time frame: at two years
Survival without disease and chronic graft-versus-host disease
Time frame: at one year post allogeneic hematopoietic stem cell transplantation
Survival without disease and chronic graft-versus-host disease
Time frame: at two years post allogeneic hematopoietic stem cell transplantation
Proportion of patient with Viral Reactivation
Reactivation of cytomegalovirus (CMV) or Epstein-Barr virus (EBV) virus
Time frame: at one year
Acute graft-versus-host disease
Time frame: at 100 days
Chronic graft-versus-host disease
Time frame: at 1 year
Chronic graft-versus-host disease
Time frame: at 2 years
Incidence of relapse
Time frame: at two years
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CHU Bordeaux
Bordeaux, France
CHU Caen
Caen, France
CHU Clermont-Ferrand
Clermont-Ferrand, France
CHU Grenoble
Grenoble, France
CHRU Lille
Lille, France
CHU Limoges
Limoges, France
CHU Lyon
Lyon, France
...and 8 more locations
Walk test
Walk tests measure the functional level of patients suffering from a wide range of cardiac, respiratory, neurological, and musculoskeletal conditions.
Time frame: at day 100
Walk test
Walk tests measure the functional level of patients suffering from a wide range of cardiac, respiratory, neurological, and musculoskeletal conditions.
Time frame: at one year
Walk test
Walk tests measure the functional level of patients suffering from a wide range of cardiac, respiratory, neurological, and musculoskeletal conditions.
Time frame: at two years
Nutritional score
Nutrional score will be assessed using the simple evaluation of food intake (SEFI scale). The minimum value is 0 and the maximum is 10. The highest score mean that the patient's food intake are the same as usual.
Time frame: at day 100
Nutritional score
Nutrional score will be assessed using the simple evaluation of food intake (SEFI scale). The minimum value is 0 and the maximum is 10. The highest score mean that the patient's food intake are the same as usual.
Time frame: at one year
Nutritional score
Nutrional score will be assessed using the simple evaluation of food intake (SEFI scale). The minimum value is 0 and the maximum is 10. The highest score mean that the patient's food intake are the same as usual.
Time frame: at two years
Karnofsky index
The Karnofsky index is a synthetic indicator of the overall health status measuring, on a scale from 0 (death) to 100 (full health)
Time frame: at day 100
Karnofsky index
The Karnofsky index is a synthetic indicator of the overall health status measuring, on a scale from 0 (death) to 100 (full health)
Time frame: at one year
Evaluation of autonomy
Autonomy will be evaluated using ADL and IADL score. Instrumental activities of daily living - global score range from 0 to 4.
Time frame: at one year
Evaluation of Quality of life
Quality of life evaluated using questionnaire "European Organization for Research and Treatment of Cancer Quality of Life Questionnaire" (EORTC QLQ-C30- v3). The QLQ-C30 is composed of both multi-item scales and single-item measures. These include five functional scales, three symptom scales, a global health status / QoL scale, and six single items. Each of the multi-item scales includes a different set of items - no item occurs in more than one scale. All of the scales and single-item measures range in score from 0 to 100. A high scale score represents a higher response level. A high score for a functional scale represents a high/healthy level of functioning. A high score for the global health status/ QoL represents a high QoL and a high score for a symptom scale/item represents a high level of symptomatology/problems. EORTC QLQ-C30 Scoring Manual. Fayers PM et al. on behalf of the EORTC Quality of Life Group. EORTC, 2001. ISBN: 2-9300.
Time frame: at one year
Length of hospitalisation initially
Time frame: at two years
Length of hospitalisation during the first year after graft
Time frame: Up to one year
Questionnaire completion rate
Time frame: At 2 years
Length of pre-grafting visit
Time frame: At 2 years
Length of D100 visit
Time frame: At 2 years
Length of 1year visit
Time frame: At 2 years
Length of 2 years visit
Time frame: At 2 years