COVID-19 and ICU-acquired MDR Bacteria

University Hospital, Lille368 enrolled

Overview

This multicenter before-after study aimed to determine the impact of infection related to SARS-CoV-2 on the incidence of ICU-acquired multidrug resistant (MDR) bacteria.

Multicenter observational before-after study, aiming to determine the impact of infection related to SARS-CoV-2 on the incidence of ICU-acquired colonization and infection related to MDR bacteria.

Study Type

OBSERVATIONAL

Enrollment

368

Conditions

Sars-CoV2 Critical Illness

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Expected ICU stay \> 48 hours * Rectal and nasal BMR screening performed \< 48 hours after admission to ICU Exclusion Criteria: * Patients aged \< 18 years Refusal to take part in the study ICU-stay \< 48 hours At least a second rectal and nasal BMR screening was not performed prior to ICU discharge (a posteriori exclusion criterion).

Locations (7)

Chu Amiens Picardie

Amiens, France

Ch Bethune

Béthune, France

Grand Hopital de L'Est Francilien

Jossigny, France

CH LENS

Lens, France

Outcomes

Primary Outcomes

Cumulative incidence of ICU-acquired colonization related multidrug resistant bacteria

percentage of patients with ICU acquired MDR bacteria colonization

Time frame: from D3 until day 28 after ICU admission

Secondary Outcomes

Cumulative incidence of ICU-acquired infection related to multidrug resistant bacteria

percentage of patients with ICU acquired MDR bacteria infection

Time frame: from D3 until day 28 after ICU admission

Mechanical ventilation duration

the number of days Under mechanical ventilation

Time frame: from D1 until day 28 after ICU admission

mortality

death in the ICU

Time frame: from D1 until day 28 after ICU admission

length of stay in intensive care unit

the number of days of hospitalization in the ICU

Time frame: from D1 until day 28 after ICU admission

Data from ClinicalTrials.gov

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