Evaluation of OSSIX® Bone in Sinus Elevation

Inclusion Criteria: 1. Patient requiring vertical elevation of the maxillary sinus. 2. Residual alveolar bone height of edentulous maxilla below the floor of the maxillary sinus of \> 4-5mm. 3. Males and females between 30-80 years old 4. Patients with healthy periodontal conditions (Treated periodontitis, PI\<25%, BoP\<25%) 5. Patients that are willing to sign an informed consent and participate in a clinical study 6. Generally fit and healthy and able to undergo oral surgical procedures under local anesthesia. 7. Teeth at the surgical site which required removal were extracted a minimum of 12 weeks prior to sinus floor elevation. Exclusion Criteria: 1. Patients who smoke over 5 cigarettes/day 2. Pregnancy (confirmed by verbal inquiry) 3. Chronic systemic pathologies (e.g. diabetes) and neoplastic of the Oro-Facial District 4. 4. Patients taking bisphosphonates 5. Any sites where an implant already failed sites 6. Untreated Periodontitis 7. Dental sites with acute infections 8. Chronic inflammatory diseases of the oral cavity 9. Autoimmune diseases (cortisone intake) 10. Allergy declared to one or more medicaments to be used during treatment 11. Alcoholics patients and/or drug addicts 12. Patients with known collagen hypersensitivity. 13. Patients with sensitivity to porcine-derived materials. 14. History or malignant tumours of the maxillary sinus 15. History of local radiation therapy