NIPE monitor is the recently developed pediatric version of the ANI monitor, which is used in adults to monitor analgesia during general anesthesia. In adults, under general anesthesia, ANI decreases after a nociceptive stimulation. The amplitude of this decrease is related to the intensity of the stim. This study aims to investigate if NIPE index decreases in the same manner after stimulations in anesthetized children.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
34
NIPE monitor connected to the anesthetic station. No part of the device in contact with the patient. No action on patient or anesthesia. Automatic recording of Heart rate and NIPE index during the study period.
Three tetanic stimulations will be performed (10-30 and 60 milliamps) under general anesthesia, before surgical incision. Stims performed via the muscle relaxation monitor (used in standard practice in this population) Each stim lasts for 5 seconds. Interval between two stims : 3-5 minutes Order on intensities randomized by a latin square of order 3.
Hopital Roger Salengro, CHU Lille
Lille, France
Variation of NIPE index (∆NIPE)
∆NIPE = \[NIPE minimal value in the 3 minutes following the stim\] - \[NIPE before stim\] NIPE varies from 0 to 100. Monitor displays one value per second. NIPE index expected to decrease after stim.
Time frame: 3 minutes following tetanic stimulation
Heart rate Variation (∆HR)
∆HR = \[HR maximal value in the 3 minutes following the stim\] - \[HR before stim\] Heart rate expected to increase after stim.
Time frame: 3 minutes following tetanic stimulation
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