Seroprevalence of SARS CoV 2 Antibodies in Previously Undiagnosed Healthcare Workers

Mayo Clinic300 enrolled

Overview

The purpose of this study is to identify healthcare workers with SARS CoV 2 antibodies who have not been previously diagnosed and are presumed COVID-19 negative, then determine the level of immunity in this population which could inform further decisions about widespread antibody testing in a healthcare worker population.

Enrolled participants will complete a survey gauging their level of confidence they will be antibody positive. Participants will then complete serologic testing for SARS CoV 2 IgG antibodies. The study will characterize the prevalence of antibody positivity in this population and assess whether there is a correlation between a pre-test confidence level using a Likert scale and actual antibody positivity.

Study Type

INTERVENTIONAL

Allocation

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

300

Conditions

SARS-CoV 2 COVID-19

Interventions

Serologic testingOTHER

COVID19 IgG antibody testing to be performed

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years old. * Mayo Clinic employee in procedural and surgical area. * Suspected COVID-19 exposure. * Completed PCR test twice with negative results. Exclusion Criteria: \- Refusal to participate in this study.

Locations (1)

Mayo Clinic in Florida

Jacksonville, Florida, United States

Outcomes

Primary Outcomes

Number of Participants With COVID-19 Antibodies

Presence of IgG antibodies detected

Time frame: 1 month

Secondary Outcomes

Ability to Predict Immune Status/Antibody Positivity

Survey of participants to gauge their confidence they will be antibody positive

Time frame: Single point in time prior to COVID-19 Antibody testing

Data from ClinicalTrials.gov

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