This study aims to investigate outcomes and predictors of outcome after extracorporeal membrane oxygenation (ECMO) therapy for severe acute respiratory syndrome (ARDS) in COVID-19 patients.
We evaluated the outcome of adult patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) requiring the use of extracorporeal membrane oxygenation (ECMO).
Study Type
OBSERVATIONAL
Enrollment
132
Veno-venous or veno-arterial extracorporeal oxygenation
Helsinki University Hospital
Helsinki, Finland
University Hospital Jean Minjoz
Besançon, France
Nancy University Hospital
Nancy, France
Henri Mondon Unoversity Hospital
Paris, France
In-hospital mortality
All-cause mortality
Time frame: Immediately after the intervention/procedure/surgery
Death on ECMO
Death during ECMO therapy
Time frame: During the intervention/procedure/surgery
Stroke
Stroke was defined as any focal or global neurological syndrome caused by ischemia and/or hemorrhage not resolving within 24 hours.
Time frame: Immediately after the intervention/procedure/surgery
Blood stream infection
Blood stream infection detected on blood cultures
Time frame: Immediately after the intervention/procedure/surgery
Lung complications requiring surgical treatment
Pneuthorax, pneumonia and/or abscess requiring surgical treatment
Time frame: Immediately after the intervention/procedure/surgery
Blood transfusion
Transfusion of red blood cells
Time frame: Immediately after the intervention/procedure/surgery
Acute kidney injury
Acute renal failure according to the Kidney Disease: Improving Global Outcomes classification (KDIGO) criteria
Time frame: Immediately after the intervention/procedure/surgery
Duration of mechanical ventilation
Duration of mechanical ventilation
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Robert Debré University Hospital
Reims, France
Hamburg University Heart Center
Hamburg, Germany
Münster University Hospital
Münster, Germany
S. Orsola Hospital
Bologna, Italy
Lecco Hospital
Lecco, Italy
Karolinska University Hospital
Stockholm, Sweden
...and 1 more locations
Time frame: During index hospital stay follow-up until 1 year after ECMO initiation
Deep vein thrombosis
Thrombosis of lower limb deep venous system
Time frame: Immediately after the intervention/procedure/surgery
Pulmonary embolism
Pulmonary embolism
Time frame: Immediately after the intervention/procedure/surgery
Length of intensive care unit stay
Length of stay in the intensive care unit
Time frame: Immediately after the intervention/procedure/surgery
Length of hospital stay
Length of hospital stay
Time frame: Immediately after the intervention/procedure/surgery
Death after hospital discharge
All-cause death
Time frame: Up to 6 months