To Explore the Effect of GH on Outcomes of IVF and Telomerase Activity of Granulosa Cells in Women With POR

Inclusion Criteria: For patients with poor ovarian response, the criteria is based on POSEIDON criteria\[1\]: 1. low ovarian reserve(AMH \<1.2ng/ml, or AFC \<5); 2. younger than 40. For patients with normal ovarian reserve, the criteria is as follow: 1. Patients who are between 20-40 years old; 2. clinical diagnosis of non-functional fallopian tube; 3. regular menstrual cycles. Exclusion Criteria: 1. BMI ≥28kg/m2; 2. medical diseases such as endocrine and metabolic diseases, autoimmune disease, etc; 3. ovarian neoplasm that ≥4 cm in diameter and has no clear pathological diagnosis by surgery; 4. adenomyosis or endometriosis confirmed by surgery; 5. untreated abnormal intrauterine environment, such as uterine effusion, endometritis, etc; 6. untreated hydrosalpinx; 7. polycystic ovary syndrome.