HU007 Eye Drops in Patients With Dry Eye Syndrome

Inclusion Criteria: * Male and Female who over 19 years old * Those who meet below criteria at least one of two eyes 1. Those who have over than score 2 in corneal staining test-Oxford grading 2. Tear secretion test without anesthesia(Schirmer test) result would be under 10mm/5min (If the test result is 0mm/5min, it should be over than 3mm/5min on the nasal stimulation schirmer test in the same eye) 3. TBUT(Tear film break-up time) test result should be under 10sec. * Woman with no possibility of pregnancy or negative pregnancy test results at a screening visit, Women or men who have agreed to maintain at least one contraceptive method during study period * Those who could understand this study and agree to informed consent voluntarily Exclusion Criteria: * Those who have clinically significant eye disease not related to dry eye symdrome * Those who are in anti-inflammatory medication for dry eye syndrome * Medication of systemic steroid or immunosuppressant * Those who have worn contact lenses before 72hours or have to wear contact lenses or disagree not to wear contact lenses during study period * Those who have medical history with intraocular surgery 90 days before screening visit * Those who have any active ophthalmic diseases such as active allergy, anterior uveitis, stevens-johnson syndrom which could affect the surfece of eye * Those who have any autoimmune diseases * Those who need a surgery for surface elevation caused by meibomian gland dysfunction(MGD) * Those who have any medical history of corneal transplantation or neurotrophic keratitis * Those who have diagnosed with glaucoma or have an intraocular pressure over than 25mmHg at least in one of the eyes * Those who have medicated cyclosporine or steroid eye-drops 30 days before screening visit * Those who have underwent any eye correction surgery such as LASIK(Laser-assistant in situ keratomileusis) 12 months before screening visit * Those who have underwent a silicone lacrimal punctal occlusion or cauterization of the punctum excluding collagen lacrimal punctal occlusion 90 days before screening visit * Those who have a hypersensitivity reaction for cyclosporine, trehalose or protein-based medication related to investigational drug * Those who have diagnosed a psychical disorder which could affect this study * Women who is pregnant or breastfeeding or those who have a plan to be pregnant * Those who have medical history on abusing medications or alchol * Those who have received other investigational drugs/devices 30 days before screening visit * Those who are inappropriate for participating in this study according to investigator's judgement