Study of Late Fetal Loss in Poitou-Charentes. GYNE-COVID

Poitiers University Hospital28 enrolled

Overview

Maternal-fetal transmission in the second or third trimester of pregnancy of the SARS-COV-2 virus could explain some late fetal losses. Finding a cause in the context of fetal loss is essential for parents and caregivers. It helps to understand the history of the disease, to address the possible risk of a recurrence and to plan for future pregnancies. If the maternal-fetal transmission of COVID 19 is confirmed and that it is responsible for obstetric complications, a preventive action could be proposed to the patients by the preconception vaccination. The investigators are seeking to clarify the frequency of this transmission is information awaited by caregivers, women, couples in particular when the latter are in distress from late fetal loss.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

Conditions

Identification of the Mother or Fetus Contamination by SARS Cov-2 Research the Presence of Viruses at Different Sites of the Mother and the Fetus or Father

Interventions

Identification by PCR of the SARS-COV-2 virus in samples taken from the fetusDIAGNOSTIC_TEST

Identification by PCR of the SARS-COV-2 virus in samples taken from the fetus Presence of SARS-COV-2 virus in samples taken from mother and father. Circulating anti-SARS-COV-2 antibodies in the mother.

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Major patient * Patient with late spontaneous abortion (≥15 weeks of gestation) * Benefiting from a Social Security scheme * Patient who consented to participate in the study * Free subject, without tutorship, curatorship or subordination Exclusion Criteria: * Persons not benefiting from a Social Security scheme or not benefiting from it through a third party. * Concurrent participation in another clinical research study.

Outcomes

Primary Outcomes

Estimate the prevalence of SARS-CoV-2 infection in women with late fetal loss of unexplained cause.

Identification by PCR of the SARS-COV-2 virus in samples taken from the fetus

Time frame: 2 months