Investigation of the Effects of Physiotherapy in Patients With Platelet Rich Plasma (PRP) Applied Knee Osteoarthritis

Hacettepe University26 enrolled

Overview

This study evaluates effects of PRP and physiotherapy on pain, physical function and quality of life in patients with knee osteoarthritis.

PRP has been reported to have a low to moderate level of evidence in patients with knee osteoarthritis (OA) in reducing pain and improving function. Similarly, in individuals with knee osteoarthritis, exercise has been reported to be effective in reducing the pain and improving physical function of the knee OA patient in the short term, and may be even more effective with individual exercise programs. However, there is no study examining the effect of PRP and exercise together. PRP and exercise can be more effective together. The aim of our study was to investigate the effects of physiotherapy on pain, physical function and quality of life in patients with knee OA who underwent PRP injection.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Knee Osteoarthritis

Interventions

ExerciseOTHER

Exercise specific to knee osteoarthritis.

Eligibility

Sex: FEMALEMin age: 45 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Grade 2-3 according to Kellgren Lawrence osteoarthritis classification, * Patients with knee osteoarthritis who underwent PRP injection at least three days ago, * Being volunteer Exclusion Criteria: * Any intra-articular application and / or physiotherapy and rehabilitation in the last 6 months, * Have any other orthopedic problems involving the lower extremities * Having cognitive problems, * Having additional neurological, rheumatologic and / or oncological problems

Locations (1)

Hacettepe University

Ankara, Samanpazari, Turkey (Türkiye)

Outcomes

Primary Outcomes

Change from Baseline Pain Level at Six Week

Pain change will be measured throughout Study and Follow-up with Visual Analog Scale. This scale is a 100 millimeter line drawn horizontally on an A4 sheet of paper. The left end of the line shows "no pain at all", the right end shows "my pain is as bad as it could be", while the remaining part shows the intermediate values. So minimum score was 0, and maximum score was 100. The patient is asked to mark the severity of the pain on the chart. Validity and reliability were made. The minimal clinical significance difference in chronic low back pain was 20 millimeters.

Time frame: At baseline, six week

Data from ClinicalTrials.gov

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