An Diagnostic Cohort on AQP4-Immunoglobulin G Detection Kit

First Affiliated Hospital of Fujian Medical University200 enrolled

Overview

The diagnostic cohort study could will be use to verify the clinical performance of the AQP4 -immunoglobulin G detection kit and whether it has a good correlation with the clinical diagnosis results. The applicability and accuracy of the kit in clinical diagnosis will be verified according to the measured data.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Neuromyelitis Optica Spectrum Disorders

Eligibility

Sex: ALLMin age: 14 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. The patients who were diagnosed with NMOSD , and the cell-based assay was used to determine the AQP4-IgG-seropositive patients; 2. AQP4-IgG is negative in health people with age and sex matching and determined by cell-based assay; 3. Female or male, age 14-80; 4. Patients or authorized family members volunteered to participate in this study and signed informed consent. Exclusion Criteria: 1. Patients with coagulation disorders; 2. Infection-related encephalitis; 3. Immune-related encephalitis; 4. A patient with severe mental illness who cannot cooperate clinically; 5. A patient with severe jaundice.

Locations (2)

Department of Neurology,First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

Third Affiliated Hospital of Sun Yat-sen University

Guangzhou, China

Outcomes

Primary Outcomes

results of AQP4 -immunoglobulin G detection kit

The Serum test results of participants using AQP4 -immunoglobulin G detection kit

Time frame: through study completion, an average of 6 months

Data from ClinicalTrials.gov

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