This study will describe the recovery process of patients undergoing cardiac surgery during the covid-19 pandemic. This will focus on hemodynamic failure and organ dysfunction after surgery. Capturing real-world data and sharing international experience will inform the management of this complex group of patients who undergo surgery throughout the COVID-19 pandemic, improving their clinical care. This investigator-led, non-commercial, non-interventional does not collect any patient identifiable information.
Performing cardiac surgery in the context of SARS-CoV2 infection is potentially at risk of marked post-operative hemodynamic failure (shock) due to the inflammatory reaction generated by the surgery and the extracorporeal circulation associated with the viral infection. In addition, in the absence of infection, 30-50% of patients will experience acute post-operative respiratory failure due to the combined effects of extracorporeal circulation and general anesthesia. The pulmonary tropism of the virus therefore is susceptible to increase in post-operative respiratory impairment. Thus, the infection is likely to favor the occurrence of post-operative shock but also to aggravate respiratory failure and other post-operative organ failures. Therefore, the investigators designed an observational study that aims at comparing two groups of patients: * Cardiac or thoracic surgery patients with a negative Covid-19 PCR pre-operatively and in the 15 following days * Cardiac or thoracic surgery patients with a positive Covid-19 PCR in the 15 days before surgery
Study Type
OBSERVATIONAL
Enrollment
350
No description
University Hospital
Nantes, France
RECRUITINGHighest VIS (Vasoactive-Inotropic Score) in the first 12 hours postoperatively.
The VIS score correlates with mortality after cardiac surgery and reflects the degree of patient hemodynamic failure. This score is calculated as follows: ISR = Dobutamine dose in g/kg/min + 100 times the Adrenaline dose in g/kg/min + 100 times the Noradrenaline dose in g/kg/min + 10,000 times the Vasopressin dose in U/kg/min.
Time frame: 12 hours post-operatively
Post-operative organ failure
Prospective assessment of ICU outcomes until all included patients were discharged from ICU
Time frame: 5 days post-operatively
Post-operative outcome
Prospective assessment of ICU outcomes until all included patients.
Time frame: 28 days post-operatively
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