Remineralization of Early Carious Lesion Using Natural Agents Versus Bioadhesive Polymers

Inclusion Criteria: * 1\. Criteria related to patient: * Age's eligible for trial was 18- 30 years. * Patient able to read and sign the informed consent form. * Cooperative patient who are willing to participate and able to continue the schedule time of wok keep good oral hygiene throughout the study. * Healthy volunteers. * Patient with moderate and high caries index. 2. Criteria related to tooth: * Patient with at least 2 white lesions (WSL) detected clinically on the buccal surface of permanent anterior teeth, one on each side. WSL selected either due to caries or orthodontic treatment (just following deboning). * Teeth with score1, 2, 3 according to ICDAS II. * Absence of preoperative pain, no mobility \& tenderness on percussion. * Radiographically, the pre-operative inclusion criteria were absence of internal or external resorption, no periapical radiolucencies and no widening of periodontal ligament space.. Exclusion Criteria: * 1\. Criteria related to patient: * Patient with Rampant uncontrolled caries. * Patient with compromised medical history. * Pregnant or breast feeding females. * Heavy smoker. * Patient who currently received extensive fluoride regiments for treatment of WSL. * Patients who planned to move within 3 months of enrollment. * Patient with evidence of xerostomia. 2. Criteria related to tooth: * Teeth with score 4, 5 according to ICDAS II. * Teeth with periapical pathology, internal or external resorption or exhibiting any symptoms of pulp pathology. * Teeth with questionable vitality or have root canal therapy. * Teeth have been pulp capped. * Teeth with periodontal pocket and bleeding on probing. * Cracked teeth.