Clinical evaluation of a new educative tools (Smartphone application) based on impact of instrumental dead space reduction after initiation of protective ventilation during mechanical ventilation.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
20
In this condition, we will implement the protective ventilation related with gender and height . A blood gas will be performed at before protective ventilation implementation and at the end of this condition.Time condition 30 minutes
In this condition, the patient will received protective ventilation with a Heat Moisture Exchanger (HME). A blood gas will be performed at the end of this condition.Time condition 30 minutes
In this condition, the patient will received protective ventilation with a Heated humidifier. A blood gas will be performed at the end of this condition.Time condition 30 minutes
Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval
Québec, Canada
RECRUITINGPaCO2 Variation
The primary outcome is to evaluate the PaCO2 variation at the end of condition 2 (after 30 minutes with protective ventilation+ HME) and condition 4 (30 minutes after Tidal volume reduction + Heater humidifier). Variation \<= 10% of PaCO2
Time frame: 60 minutes post intervention
PaCO2 Variation
The primary outcome is to evaluate the PaCO2 variation at the end of condition 2 (after 30 minutes with protective ventilation+ HME) and condition 4 (30 minutes after Tidal volume reduction + Heater humidifier). Variation \<= 10% of PaCO2
Time frame: 120 minutes post intervention
Correlation between PCO2 variation and alveolar ventilation variation
We will compare PaCO2 level variation and the alveolar ventilation variation to establish correlation. Correlation variation under 10% will be significative
Time frame: 60 and 90 minutes post intervention
Hemodynamic impact vs pH
Cardiac echographic measurement (LeftVentricularEjectionFraction) in relation with acidosis status
Time frame: Baseline, 30, 60, 90 and 120 minutes post intervention
Hemodynamic impact vs pH
Cardiac echographic measurement (RightVentricularEjectionFraction) in relation with acidosis status
Time frame: Baseline, 30, 60, 90 and 120 minutes post intervention
Hemodynamic impact vs pH
Cardiac echographic measurement Arterial pulmonary pressure) in relation with acidosis status
Time frame: Baseline, 30, 60, 90 and 120 minutes post intervention
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
n this condition, we will reduce Tidal volume (with smartphone application calculation) to obtain the same alveolar ventilation (PaCO2) obtained on the HME condition