Background: Coronavirus disease (COVID-19) is a tremendous challenge the modern world has never seen before and is overwhelming the capacities of healthcare systems worldwide. Patients with cardiovascular diseases, heart failure in particular, and cardiovascular risk factors seem to be at a very high risk if affected by COVID-19 - and vice versa there are more and more reports of cardiac manifestations with the viral disease. Aim: The purpose of the study is to characterise the clinical course of adult inpatients with COVID-19 and concomitant cardiovascular affection in a worldwide, multicentre PCHF registry. Methods: Retrospective and prospective data analysis. Data on demographic, clinical, selected laboratory, electrocardiography and echocardiography parameters, treatment and outcome will be collected. The principal investigator provides dedicated electronic case report form. The primary outcome is in-hospital mortality. The secondary endpoints will be ICU length of stay, hospital length of stay, the need and duration of invasive mechanical ventilation, cardiovascular hospitalisation after 3 and 6 months from index hospitalisation, all-cause and cardiovascular mortality after 3 and 6 months from index hospitalisation.
Study Type
OBSERVATIONAL
Enrollment
1,500
Zurich Heart Center, Unispital Zurich
Zurich, Switzerland
RECRUITINGIn-hospital mortality.
All-cause and cardiovascular mortality during index hospitalization.
Time frame: Hospitalization period, assessed up to 30 days
The length of stay in the intensive care unit.
The duration of hospitalization on the intensive care unit.
Time frame: Hospitalization period in the ICU, assessed up to 30 days
The duration of hospitalization.
The total length of stay in the hospital.
Time frame: Hospitalization period, assessed up to 30 days
The need and duration of invasive mechanical ventilation.
Time frame: Hospitalization period, assessed up to 30 days
Hospitalization for cardiovascular causes or cardiovascular deaths within 3 months after hospitalization.
Time frame: 3 months
Hospitalization for cardiovascular causes or cardiovascular deaths within 6 months after hospitalization.
Time frame: 6 months
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