The primary intention of this study is to determine the diagnostic performance of ultra-low-dose CT (ULDCT) in diagnosis and follow-up of diffuse parenchymal lung disease (DPLD). We hypothesize that inspiratory and expiratory chest ULDCT has comparable diagnostic yield to standard dose chest High-resolution computed tomography (HRCT) and utility for follow-up of patients with known DPLD. We will study this hypothesis through the following aims: 1. Determine whether inspiratory and expiratory ULDCT are comparable to HRCT in identifying mosaic attenuation due to air-trapping. 2. Determine whether ULDCT is as good as HRCT for follow-up of patients with established DPLD to identify disease progression.
Study Type
OBSERVATIONAL
Enrollment
30
Sheba Medical Center
Ramat Gan, Israel
The primary outcome measure of this study is to determine the diagnostic performance of ULDCT in diagnosis of DPLD.
The diagnostic performance will be evaluated according to the biopsy results
Time frame: during the procedure/surgery
The primary outcome measure of this study is to determine the prognostic performance of ULDCT in the follow up of DPLD.
The diagnostic performance will be evaluated according to the biopsy results
Time frame: during the procedure/surgery
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