Transcranial Static Magnetic Field Stimulation (tSMS) in Amyotrophic Lateral Sclerosis (ALS).

Inclusion Criteria: * age between 18 and 75 years * diagnosis of ALS according to revised El Escorial criteria and Awaji-Shima criteria * disease duration \< 24 months * ALSFRS-R \> 30 at the recruitment * ALSFRS-R decline \> 1 in the at least 3-months period before the intervention * normal respiratory functionality (FVC \> 80% and ALSFRS-R items 10,11,12 \> 4) at the recruitment * treatment with riluzole 50 mg x 2/die Exclusion Criteria: * inclusion in other clinical trials * presence of tracheotomy or/and PEG (percutaneous endoscopic gastrostomy) * contraindications to magnetic fields exposure * pregnancy or breast-feeding * history of epilepsy or seizures * assumption of drugs acting on central nervous system, except for antidepressive drugs and benzodiazepines. * cognitive impairment * lack of informed consent