Routinely collected data will be used to assess the morbidity and mortality of cancer patients following a positive COVID-19 infection.
The SARS-CoV-2, (COVID-19) virus of the coronavirus family is believed to have been transmitted from animal to human. On 12th March 2020, the World Health Organisation (WHO) declared this particular coronavirus outbreak a pandemic. How COVID-19 affects people is still not widely understood. Some people who have tested positive for the virus have been asymptomatic while others, who were otherwise well and healthy before infection, have died. Currently, information obtained so far suggests that most COVID-19 illness, however older people and people with severe comorbidities such as heart and lung disease and diabetes, seem to be at higher risk of developing serious COVID-19 illness. This research is a retrospective, non-interventional study whose aim is to describe the features of COVID-19 infection specifically in cancer patients; to investigate its severity in this particular population and evaluate the long-term outcomes by means of medical charts review of consecutive patients co-diagnosed with SARS-CoV-2 infection and malignancy. Patients will be identified from electronic medical records and entered into a pre-designed database. All information used will have been previously collected as part of routine standard of care and will involve but is not limited to: blood test results, prior and current anti-cancer therapy, medical history and most importantly clinical outcomes, such as response to any treatment provided for COVID-19 and patients' survival in relation to baseline clinic-pathologic profile. All data will be collected by each patient's team and will be anonymised and stored in a password-protected NHS computer.
Study Type
OBSERVATIONAL
Enrollment
3,820
Institut Jules Bordet
Brussels, Belgium
Describe presenting characteristics and severity or SARS-CoV-2 infection in patients with cancer
Compiling a list of symptoms experienced by patients recruited onto the trial
Time frame: 2 years
Assessing what factors are involved in prognosis of cancer patients with COVID-19
Evaluate prognostic factors for survival in patients with SARS-CoV-2 infection and cancer
Time frame: 2 years
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Institut Gustave Roussy
Villejuif, France
Ludwig-Maximilians-Universität München
Munich, Germany
Azienda Ospedaliero Universitaria SS. Antonio e Biagio e Cesare Arrigo
Alessandria, Italy
ASST Azienda Ospedaliera Papa Giovanni XXIII
Bergamo, Italy
Azienda Ospedaliera Spedali Civili di Brescia
Brescia, Italy
Fondazione Poliambulanza Istituto Ospedaliero
Brescia, Italy
Azienda Istituti Ospitalieri di Cremona
Cremona, Italy
Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Italy
Humanitas Research Hospital
Milan, Italy
...and 15 more locations