Structural Orbital Changes in Anophthalmic Socket Syndrome

N/ACompletedNCT04395404

Universitaire Ziekenhuizen KU Leuven10 enrolled

Overview

Understand better the aetiology and physiopathogenesis of anophthalmic socket syndrome.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Anophthalmos; Acquired Anophthalmic Socket Syndrome

Interventions

MRIDIAGNOSTIC_TEST

Patients with unilateral ASS, with and without the prosthesis in situ, are analysed by 3D- magnetic resonance imaging (MRI) with 64 channel head coil using T1 and T2 weighted, DIXON/ IDEAL, and T2 inversion recovery sequences.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 years or older * Unilateral anophthalmic socket syndrome (superior sulcus grading 0 till 4) * Enucleation/evisceration with primary implant more than 5 years ago * After informed consent Exclusion Criteria: * MRI absolute and relative contraindications such as metallic fragments or metallic containing devices, * history of orbital trauma, previous anophthalmic socket and eyelid surgery, inflammation, infection, buphthalmos, congenital anophthalmos and radiation

Locations (1)

UZ Leuven

Leuven, Belgium

Outcomes

Primary Outcomes

Displacement of orbital structures

mm in x,y,z axis

Time frame: At least 5 years after enucleation or evisceration

Volumetric orbital difference

Time frame: At least 5 years after enucleation or evisceration

Surface comparisson of bony orbits

Time frame: At least 5 years after enucleation or evisceration

Data from ClinicalTrials.gov

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