This is observational study to assess the prognosis of patients hospitalized with COVID-19 confirmed by RT-PCR and exposed to trimethylxanthine (TMX). Trimethylxanthine is the active molecule present in coffee. Due to the lack of etiologic treatments and considering interest about old treatments as an avenue for research, we conducted a comparative study aiming to evaluate the effect of 1,3,7-trimethylxanthine on COVID-19 infected patients. This is actually a study about methodology. The objective of this study is therefore not to demonstrate the effect of the substance on the disease but the importance of a rigorous methodology in scientific research. This project is called "Method and Teaching of Scientific Studies".
Study Type
OBSERVATIONAL
Enrollment
93
Only data collection
Comparison of vital status
the patient clinical status at day 6 after hospital admission, defined as alive, or dead.
Time frame: 6 days
Comparaison of duration of hospital stay
Time frame: 6 days
Comparaison of severity
Evaluated by National Early Warning Score from 0 to 20, 20 being the worst score, with a high risk of death.
Time frame: 6 days
Comparaison of secondary effects (adverse events that needed disruption of treatment (anemia, tachycardia, osteoporosis) : secondary effects of coffee).
with
Time frame: 6 days
Comparaison of use of antibiotics
Time frame: 14 days after hospital admission.
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