The protection of cochlear cells is one of the main concerns of cochlear implant surgery. New electrode designs or additional molecules have been used for this purpose. The aim of the study is to test the effect of dexamethasone in two different application methods.
The protection of cochlear cells is one of the main concerns of cochlear implant surgery. New electrode designs or additional molecules have been used for this purpose. The aim of the study is to test the effect of dexamethasone in two different application methods. Participants who will have cochlear implant surgery will be divided into three groups. Group 1 will have intracochlear dexamethasone after the incision of the round window membrane. Group 2 will have intratympanic dexamethasone after the incision of the round window membrane. Group 3 will serve as a control group. All participants will be tested after a week, a month, 3, and 6 months. Impedance and threshold measurements will be compared.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
34
intracochlear injection of dexamethasone with cochlear implantation
intratympanic injection of dexamethasone with cochlear implantation
Control group: No drugs will be injected middle ear with cochlear implantation
Pamukkale University
Denizli, Turkey (Türkiye)
Electrode Impedance(Ohm)
All intra-operative impedance values will be acquired after surgery. They will be repeated in first and 3 rd months
Time frame: 1-3 months
Electrode thresholds(CL)
All intra-operative thresholds will be acquired after surgery. They will be repeated in first and 3 rd months
Time frame: 1-3 months
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