The purpose of this study is to assess whether quadratus lumborum (QL) block performed 1 day after cesarean delivery will provide supplemental post-cesarean analgesia and reduce opioid requirements.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
0.9% saline on each side
0.25% bupivacaine (50mg) on each side
3mg preservative-free dexamethasone on each side
The University of Texas Health Science Center at Houston
Houston, Texas, United States
Total opioid consumption
Time frame: 48 hours after intervention
Amount of opioids used
Time frame: at the time of intervention (one day following cesarean delivery)
Amount of opioids used
Time frame: 6 hours after intervention
Amount of opioids used
Time frame: 12 hours after intervention
Amount of opioids used
Time frame: 24 hours after intervention
Amount of opioids used
Time frame: 48 hours after intervention
Time from quadratus lumborum block until first opioid request
Time frame: from time of intervention until time of first opioid request (up to 48 hours)
Pain as measured by an 11-point verbal pain score (at rest)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: at the time of intervention (one day following cesarean delivery)
Pain as measured by an 11-point verbal pain score (with movement)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: at the time of intervention (one day following cesarean delivery)
Pain as measured by an 11-point verbal pain score (at rest)
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The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: 6 hours after intervention
Pain as measured by an 11-point verbal pain score (with movement)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: 6 hours after intervention
Pain as measured by an 11-point verbal pain score (at rest)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: 12 hours after intervention
Pain as measured by an 11-point verbal pain score (with movement)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: 12 hours after intervention
Pain as measured by an 11-point verbal pain score (at rest)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: 24 hours after intervention
Pain as measured by an 11-point verbal pain score (with movement)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: 24 hours after intervention
Pain as measured by an 11-point verbal pain score (at rest)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: 48 hours after intervention
Pain as measured by an 11-point verbal pain score (with movement)
The 11-point verbal pain score ranges from 0-10, with a higher number indicating worse pain.
Time frame: 48 hours after intervention
Nausea as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: at the time of intervention (one day following cesarean delivery)
Nausea as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 6 hours after intervention
Nausea as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 12 hours after intervention
Nausea, pruritus and sedation as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 24 hours after intervention
Nausea as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 48 hours after intervention
Pruritus as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: at the time of intervention (one day following cesarean delivery)
Pruritus as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 6 hours after intervention
Pruritus as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 12 hours after intervention
Pruritus as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 24 hours after intervention
Pruritus as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 48 hours after intervention
Sedation as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: at the time of intervention (one day following cesarean delivery)
Sedation as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 6 hours after intervention
Sedation as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 12 hours after intervention
Sedation as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 24 hours after intervention
Sedation as measured by a 3-point scale
This is measured categorically as none, mild, or moderate-severe.
Time frame: 48 hours after intervention
Patient satisfaction as measured by the 5-point Likert scale
The 5-point scale ranges from extremely satisfied to not satisfied.
Time frame: 48 hours after intervention