Endotracheal Tube Cuff Pressure Measurement

Bagcilar Training and Research Hospital30 enrolled

Overview

The effect of endotracheal cuff pressure measurement technique for preventing ventilatory associated pneumonia.

Aim of this study is to evaluate the effect of endotracheal cuff pressure measurement technique for preventing ventilatory associated pneumonia of severe traumatic brain injured patients in a tertiary level intensive care unit.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Ventilator Associated Pneumonia Morality Trauma, Brain Endotracheal Aspiration

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: Patients with ASA classification of 1 - 2- 3 patients Patients required mechanical ventilation support for more than 48 hours Patients diagnosed with Traumatic brain injury Exclusion Criteria: Official patient relatives who rejected to give informed consent for the study Patients diagnosed with aspiration pneumonia during ICU follow up Patients diagnosed with Acute Respiratory Distress Syndrome Patients diagnosed with cavitary lung lesion Primary lung cancer Metastatic lung cancer Congenitally immune deficiency Leukopenia Neutropenia Tracheostomized patients Post cardiopulmonary arrest patients Pregnancy

Locations (1)

Bagcilar Training and Research Hospital

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Duration

Follow up duration in ICU

Time frame: 30 days

Ventilation

Mechanically ventilated period

Time frame: 30 days

Score

Clinical Pulmonary Infection Score Change from baseline at 48.hour, 72.hour and 96.hour

Time frame: 48.hour - 72.hour - 96.hour

CRP

C Reactive Protein measurement change from Baseline at 48.hour, 72.hour and 96.hour

Time frame: 48.hour - 72.hour - 96.hour

Oxygenation

Fractional Inspiratory Oxygen levels change from baseline at 48.hour, 72.hour and 96.hour

Time frame: 48.hour - 72.hour - 96.hour

PEEP

Positive End Expiratory Pressure levels change from baseline at 48.hour, 72.hour and 96.hour during ventilatory support

Time frame: 48.hour - 72.hour - 96.hour

Secondary Outcomes

Tracheal aspirate

Tracheal aspirate sample for culture

Time frame: 0.hour - 48.hour - 72.hour - 96.hour

Bacterial distribution

Bacterial distribution of tracheal aspirate culture

Time frame: 0.hour - 48.hour - 72.hour - 96.hour

Mortality

Total mortality ratio during study period

Data from ClinicalTrials.gov

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