The study aims to evaluate the efficacy of a modified Banxia Xiexin Decoction (BXD) for Wei-Pi through a randomized, waitlist controlled trial.
After being informed about the study plan, potential risk and benefits, all subjects will give written informed consent prior to participation and undergo eligibility screening. Eligible participants will be randomized, in a 1:1 ratio, into BXD group and waitlist group.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
88
A modified Banxie Xiexin Decoction based on Chinese medicine syndrome differentiation.
Hong Kong Buddhist Association - The University of Hong Kong Chinese Medicine Clinic cum Training and Research Centre (Wong Tai Sin District)
Hong Kong, Hong Kong
Change of the Quality of Life Questionnaire for Functional Digestive Disorders
Quality of Life Questionnaire for Functional Digestive Disorders (FDDQL)
Time frame: Change from baseline score at 3 weeks.
The Hospital Anxiety and Depression Scale
The Hospital Anxiety and Depression Scale (HADS) consists of 14 items. Each item is scored from 0-3. Total score ranges between 0 and 21 for either anxiety or depression.
Time frame: Weeks 0, 3, and 7
EQ-5D-5L
EuroQoL 5-dimension 5-level
Time frame: Weeks 0, 1, 2, 3, 4, and 7
Liver function test
Serum Alanine transaminase (ALT) and Aspartate transaminase (AST).
Time frame: Weeks 0 and 3.
Kidney function test
Estimated Glomerular Filtration Rate (eGFR)
Time frame: Weeks 0 and 3.
Quality of Life Questionnaire for Functional Digestive Disorders
Quality of Life Questionnaire for Functional Digestive Disorders (FDDQL)
Time frame: Weeks 0, 3, and 7
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