The proposed study looks at the effect of long-term diet modification with or without full-fat dairy products or restrictive eating on body weight, body composition and cardiometabolic markers in healthy overweight/obese men and women.
A total of 93 males and females will participate in the study at the University of Toronto. At the beginning and after 12 weeks, body weight, composition will be measured through Bodpod scans. Resting metabolic rate and thermogenesis will be measured by indirect calorimetry. Also, fecal samples will be collected for gut microbiome profiling along with blood for glucose, insulin, hormones, triacylglycerol, HbA1c, short-chain fatty acid, red blood cells and FGF21. Urine samples will be collected throughout the study. A followup session at 16 weeks will reassess previous measures.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
93
Full-fat milk (3.25% milk, 250 mL), assortment of yogurts, and cheeses
Dietitian will assist with 500 kcal/day reduction through limiting of macronutrients 45-65% energy from carbohydrates 20-35% energy from fat 10-35% energy from protein
Mount Saint Vincent University
Halifax, Nova Scotia, Canada
Department of Nutritional Sciences
Toronto, Ontario, Canada
Change in body weight
Each participant will attend 8 sessions biweekly in total
Time frame: Starting at the beginning of the study 0 week then biweekly for 7 sessions up to 12 weeks with a followed up at 16 weeks.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.