Short Therapy for Febrile UTI in Childhood

Inclusion Criteria: 1. Age from 3 months to 5 years; 2. Clinical diagnosis of febrile UTI, defined by fever ≥38°C and positive result of urinalysis (nitrite and/or leukocyte esterase positivity) in two consecutive urine samples collected by bladder catheterization or clean catch (19). The diagnosis of UTI will be then confirmed by positive urine culture for a single type of bacterium with a charge\> 105 CFU /ml as per the Recommendations of the Italian Society of Pediatric Nephrology (SINePe) (19). Exclusion Criteria: 1. "Complicated" febrile UTI (septic appearance, repeated vomiting impeding oral administration of the antibiotic, severe-moderate dehydration with the need for intravenous antibiotic therapy) 2. Presence of an inserted urinary catheter 3. Immunodeficiency 4. Hypersensitivity to the active substance or other beta-lactam antibiotics 5. Any antibiotic treatment received in the previous 15 days. 6. Presence of another poorly controlled chronic medical condition (diabetes, inflammatory bowel disease, etc.) 7. Presence of neurological bladder 8. Presence of phenylketonuria or glucose-galactose malabsorption 9. Intestinal malabsorption 10. Poor compliance 11. History of jaundice or liver failure positive