Study KBP-2020-CPHG Documenting New Cases of Primary Lung Cancer (PLC) Diagnosed in Respiratory Medicine Departments and Lung Cancer Units at General Hospitals From January 1st to December 31st 2020

N/AUnknownNCT04402099

Collège des Pneumologues des Hôpitaux Généraux10,000 enrolled

Overview

Twenty years after KBP-2000-CPHG study and ten years after KBP-2010-CPHG study, the CPHG proposes to conduct a new epidemiological study on primary PLC in order to evaluate and analyze the changes that have occurred over the last decade. Primary endpoint: Estimate 1-year- and 5-year-mortality rates in patients with PLC. Secondary endpoints: * Describe PLC patient population managed by pulmonologists at French General Hospitals in 2020 * Describe PLC diagnostic and therapeutic management by pulmonologists at French General Hospitals in 2020 and compare them to KBP-2000-CPHG and KBP-2010-CPHG studies * Estimate prognostic factors * Compare patient and tumor characteristics to those observed for KBP-2010-CPHG and KBP-2000-CPHG studies * Compare observed survival rates to those reported for KBP-2000-CPHG and KBP-2010-CPHG studies

Study Type

OBSERVATIONAL

Enrollment

10,000

Conditions

Lung Cancer

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years * Primary Lung Cancer histologically (or cytologically or presence of a mutation on liquid biopsy with compatible imaging) proven between January 1st and December 31st, 2020\* * Follow-up by a lung specialist at a General Hospital * Oral informed consent \* date of collected sample Exclusion Criteria: * Age \< 18 years * Secondary lung cancer * Recurrence of same histological type PLC- left to the investigator discretion according to the clinic and the imagery * Previous enrolment in the study * Freedom deprived patient following a legal or administrative decision * Patient unable to give his(her) consent

Locations (1)

Outcomes

Primary Outcomes

Estimate 1-year mortality rates in patients with PLC.

Global survival at 1 year

Time frame: 1 year

Estimate 5-year mortality rates in patients with PLC.

Global survival at 5 years

Time frame: 5 years

Secondary Outcomes

Describe PLC patient population managed by pulmonologists at French General Hospitals in 2020

\- Patient data: age, gender, birth location, height, weight, comorbidity score, smoking status, cannabis uptake, Performance Status, and death

Time frame: 1 year

Describe PLC diagnostic and therapeutic management by pulmonologists at French General Hospitals in 2020 and compare them to KBP-2000-CPHG and KBP-2010-CPHG studies

\- Disease data: diagnostic method, anatomopathological classification, PDL-1 status, molecular biology test, tumor mutation burden, TNM classification, and stage (8th edition)

Time frame: 1 year