Redo Surgery or Transcatheter Valve-in-Valve for Mitral Bioprosthetic Dysfunction (SURViV)

Inclusion Criteria: * Age\>18 years; * Symptoms of heart failure NYHA class\>ll; * Severe mitral bioprosthetic dysfunction (stenosis, regurgitation, mixed) defined by echocardiography; * Heart team (including cardiac surgeon) agree on eligibility including assessment that transeptal, transcatheter mitral valve replacement (TsMVR) and redo surgical mitral valve replacement (rSMVR) are appropriate; * The study patient or the study patient's legal representative informed of the nature of the study, agreed to its provisions and provided written informed consent as approved by the Institutional Review Board (IRB) center; * The study patient agreed to comply with all required post- procedure follow-up visits including annual visits through 10 years and analysis close date visits, which was conducted as a phone follow-up; * Heart team agreed (a priori) on treatment strategy for concomitant coronary disease (if present); * Patient agreed to undergo redo surgical mitral valve replacement (rSMVR) if randomized to control treatment. Exclusion Criteria: * Heart Team assessment of inoperability (including examining cardiac surgeon); * Hostile chest; * Evidence of an acute myocardial infarction \< 1 month (30 days) before the intended treatment \[defined as: Q wave Ml, or non-Q wave Ml with total creatine kinase (CK), creatine kinase MB isoform (CK-MB) and/or cardiac troponin elevations (WHO definition)\]; * Concomitant severe valvular disease (aortic, tricuspid or pulmonic) requiring surgical intervention; * Mitral mechanical prosthesis or mitral valve rings; * Preexisting mechanical or bioprosthetic valve in other position with severe dysfunction; * Complex coronary artery disease: unprotected left main coronary artery, Syntax score \> 32 (in the absence of prior revascularization); * Any therapeutic invasive cardiac procedure resulting in a permanent implant that is performed within 30 days of the index procedure (unless part of planned strategy for treatment of concomitant coronary artery disease). Implantation of a permanent pacemaker is not an exclusion criteria; * Patients with planned concomitant surgical or transcatheter ablation for atrial fibrillation; * Leukopenia (WBC \< 3000 cell/mL), acute anemia (Hgb\< 9 g/dL), thrombocytopenia (Pht\< 50,000 cell/mL); * Hypertrophic cardiomyopathy with or without obstruction (HOCM); * Predicted neo-LVOT area \< 170 mm2 without feasible augmentation strategies; * Severe ventricular dysfunction with left-ventricular ejection fraction (LVEF) \< 20%; * Echocardiographic evidence of intracardiac mass, thrombus or vegetation; * Active upper gastrointestinal (GI) bleeding within 3 months (90 days) prior to procedure; * A known contraindication or hypersensitivity to all anticoagulation regimens, or inability to be anticoagulated for the study procedure; * Clinically (by neurologist) or neuroimaging confirmed stroke or transient ischemic attack (TIA) within 3 months (90 days) of the procedure; * Renal insufficiency (creatinine \> 3.0 mg/dL) and/or renal replacement therapy at the time of screening; * Estimated life expectancy \< 24 months (730 days) due to carcinomas, chronic liver disease, chronic renal disease or chronic end stage pulmonary disease; * Currently participating in an investigational drug or another device study; * Active bacterial endocarditis within 6 months (180 days) of procedure; * Patient refuses redo mitral valve replacement surgery. * Pregnancy