Chlorhexidine is a effective strategy in reducing ventilator associated pneumonia. However, it is unclear if prophylactic 0.12% chlorhexidine oral rinse can reduce the risk of non-ventilator hospital-acquired pneumonia among hospitalized patients.
Participants will be classified into three groups, applied twice a day by care givers. Oral colonization will be tested in the baseline, day-3, day-7, and at the discharge. Quantitation of colonization of the oral cavity by oral rinses and respiratory pathogens were measured.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
103
The intervention group 1 received 10ml 0.12% chlorhexidine solution for oral rinse twice a day.
The intervention group 2 received 10ml Listerine solution for oral rinse twice a day.
The control group received 10ml normal saline for oral rinse twice a day.
Yen-Chin Chen
Tainan, Taiwan
oral bacterial colonization status
Time frame: 1 year
The rate of non-ventilator associated pneumonia
Time frame: 1 year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.