Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis

Mansoura University900 enrolled

Overview

The ideal timing for ELC continues to be debatable in patients with acute calculator cholecystitis (ACC). This study was planned to identify the impact of different ELC timing in ACC on surgical outcomes in terms of safety and efficacy

This multicentric analysis involved of successive patients with ACC ELC between April 2018 and March 2020. Patients were divided into three groups according to the timing of the surgery: from the onset of symptoms within the first 3 days (group 1), between 4 and 7 days (group 2), and beyond 7 days (group 3). The primary outcome was the incidence of postoperative complications The secondary outcomes were conversion rate, blood loss, operative times, operational difficulty, the cost-benefit relationship, postoperative stay with each treatment line.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

900

Conditions

Acute Cholecystitis

Interventions

from the onset of symptoms within the first 3 daysPROCEDURE

ELC within 3 days of onset of ACC

: from the onset of symptoms within the 4-7 daysPROCEDURE

ELC 4-7days of onset of ACC

from the onset of symptoms beyond 7 daysPROCEDURE

ELC after 7days of onset of ACC

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: ACC patients who underwent early LC Exclusion Criteria: Pregnancy, Acalculous cholecystitis, CBDS, Ascending cholangitis, Pancreatitis, ASA score 4, Patients scheduled for DLC with failed medical treatment.

Locations (1)

Mohamed Attea

Al Mansurah, Egypt

Outcomes

Primary Outcomes

the incidence of postoperative morbidity

the incidence of postoperative morbidity during the 30th day of postoperative procedure

Time frame: 30 DAYS

Secondary Outcomes

conversion rate

conversion rate to open cholecystectomy

Time frame: INTRAOPERATIVE

blood loss

Time frame: intraoperative

hospital stay

overall hospital stay

Time frame: 30 days

Data from ClinicalTrials.gov

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